Mission
The mission of the Adeline Yen Mah Vaccine Center is to drive interdisciplinary innovation at the intersection of nucleic acid biology, systems biology, immunoengineering, and advanced nanoparticle delivery to develop next-generation vaccines, gene therapies, and nucleic acid-based therapeutics. By integrating cutting-edge mRNA technologies, lipid nanoparticle platforms, adjuvant engineering, and advanced immunologic profiling with translational infrastructure, the Center accelerates the path from molecular design to clinical application to address emerging infectious diseases, cancer, genetic disorders, and other unmet medical needs.
Vision
Our vision is to shape the future of medicine through breakthroughs in vaccines, gene therapies, and translational immunology for the prevention and treatment of infectious and chronic diseases.
Organizationl Structures
Latest News
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Speaker Event: Alvin Yu PhD “Molecular Simulations of HIV-1 Maturation”
Alvin Yu, PhD will be giving a seminar on Molecular Simulations of HIV-1 Maturation. For more info, 🔗 Read More →
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2026 Faculty Retreat: Future Directions for Biomedical Research
The 2026 Faculty Research Retreat at the University of California, Irvine School of Medicine spotlighted bold ideas shaping the future of biomedical science. From AI-driven healthcare to breakthroughs in genomics and stem cell research, faculty shared innovations with real-world impact. The event captured UCI’s momentum—and a glimpse of what’s next. 🔗 Read More →
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New Findings Reshape Our Understanding of Human T Cell Biology
Scientists at UC Irvine have uncovered a surprising truth about where most of your immune system actually operates—and it’s not where researchers have been looking. This breakthrough challenges long-held assumptions and hints at a much deeper level of complexity in how the body fights disease. What they found could change the future of vaccines and…
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UC Irvine Receives Initial $33 Million in Federal Support for Vaccine Research
The UCI Vaccines for Pandemic Preparedness Center (VPPC) receives NIH funding to prepare for pandemic threats in the future. The Center will conduct basic and translational research to produce prototype vaccines against members of the Picornaviridae and Peribunyaviridae virus families.
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Adeline Yen Mah Vaccine Center Director Phil Felgner Awarded Princess of Asturias Award
The Princess of Asturias Foundation convenes the Princess of Asturias Awards, which are presented at an academic ceremony held each year in Oviedo, capital of the Principality of Asturias. The Foundation’s aims are to contribute to extolling and promoting those scientific, cultural and humanistic values that form part of the universal heritage of humanity and…
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In the Press: UC Irvine Researchers Launch COVID-19 Antibody Study in Santa Ana
🔗 UC Irvine Researchers Launch COVID-19 Antibody Study in Santa Ana → 🔗 Estimated Seroprevalence of Sars-Cov-2 Antibodies Among Adults in Orange County, California →