Mission
The mission of the Adeline Yen Mah Vaccine Center is to drive interdisciplinary innovation at the intersection of nucleic acid biology, systems biology, immunoengineering, and advanced nanoparticle delivery to develop next-generation vaccines, gene therapies, and nucleic acid-based therapeutics. By integrating cutting-edge mRNA technologies, lipid nanoparticle platforms, adjuvant engineering, and advanced immunologic profiling with translational infrastructure, the Center accelerates the path from molecular design to clinical application to address emerging infectious diseases, cancer, genetic disorders, and other unmet medical needs.
Vision
Our vision is to shape the future of medicine through breakthroughs in vaccines, gene therapies, and translational immunology for the prevention and treatment of infectious and chronic diseases.
Latest News
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Coronavirus Publications – 4/18/2020 Two
Our latest SARS-CoV-2 BioRxiv preprints from UC Irvine Adeline Yen Mah Vaccine Center: Analysis of Serologic Cross-Reactivity Between Common Human Coronaviruses and SARS-CoV-2 Using Coronavirus Antigen Microarray Analysis of SARS-CoV-2 Antibodies in COVID-19 Convalescent Plasma using a Coronavirus Antigen Microarray
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Coronavirus Publications – 4/18/2020 One
๐ Doctors Race to Develop Coronavirus Drugs, Speeding Through Hurdles โ ๐ Nanommune Inc. to Develop and Market a Novel Coronavirus Multiplex Serological Assay โ ๐ Could a Blood Test for Coronavirus Antibodies Get California Back to Normal? Lots of Questions Remain โ ๐ Where California Stands With Coronavirus Testing Right Now โ ๐ Darpa-Funded…
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UCI Tech Can Provide Better Understanding of COVID-19 and Vaccine Possibilities
Researchers at the University of California, Irvine are advancing new technologies to better understand COVID-19 and speed vaccine development. From antibody testing to immune system mapping, these tools reveal how the body responds to infection. Their work offers promising insights that could shape future pandemic responses.
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Mass Testing Is the Only Sustainable Solution to the Coronavirus
Mass testing is framed as the clearest path to controlling COVID-19 without long-term shutdowns. By identifying who is infected and who has immunity, society can reopen more safely. The approach is ambitiousโbut it offers a practical way forward. ๐ The U.S. faces two disastrous scenarios. There’s a third option. โ A TWiV foursome provides an…
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How to Protect Yourself Against the Coronavirus
Dr. Peter Hotez of Baylor University on symptoms, treatment and a vaccine. ๐ Watch โ
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You Are Unvaccinated and Got Sick. These Are Your Odds.
Vaccine hesitancy is shaped less by ignorance than by trust, identity, and lived experience. The article argues that simply correcting misinformation is not enough to change minds. Instead, it calls for more empathetic, trust-based communication to address concerns and build confidence in vaccines. ๐ Read More โ
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