Labs
Phil Felgner (Director)
Novel Antigens Discovery and Vaccine Formulations
The Felgner Lab pioneers vaccine research, developing recombinant protein-adjuvant and mRNA-lipid nano particle (LNP) vaccines that trigger protective immune responses. The work extends to cancer treatments, vaccines for global infections, and pandemic preparedness, in collaboration with leading labs, universities, and companies.
David Huw Davies (Assistant Director)
Immunology and Vaccine Development
The Davies Lab focuses on improving vaccine effectiveness, with a special emphasis on influenza vaccines.The lab focuses on innovative strategies to strengthen and expand immune responses, including multivalent formulations, nanoparticle delivery, and combination adjuvants.
Shivashankar Othy
Spatiotemporal Dynamics of Immune Regulation
The Othy lab focuses on immune regulation at the organismal, cellular, and molecular levels, with the goal of uncovering networks critical to human health and disease.
Lisa Wagar
Translational Human Immunology Laboratory
The Wagar lab studies immune organoids from human tissues to understand adaptive immunity. Their goals are to expand vaccine research, uncover immune regulation mechanisms, and explain vaccine response variability. By focusing on host and antigen design, they aim to improve vaccine development and immune understanding.
Szu-Wen Wang
Designing of Biologically Inspired Materials
Our laboratory pioneers the design of cutting-edge functional materials inspired by nature's ingenuity. These advanced biomaterials unlock groundbreaking strategies for tackling critical health challenges, including cancer treatment, innovative drug delivery systems, and transformative regenerative medicine.
Alvin Yu
The Computational Biophysics Group (CBG)
The Computational Biophysics Group (CBG) at UCI develops theoretical and computational methods to study complex biological systems.